ArticleWorld journal of gastrointestinal surgery2026
Preoperative clinical and laboratory factors associated with early complications after low anterior resection: Exploratory analysis of the eosinophil/lymphocyte ratio.
Article in World journal of gastrointestinal surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundRectal cancer is of particular importance among colorectal malignancies due to technical difficulties in surgical treatment and serious complications that can occur postoperatively.
aimTo determine the probable factors affecting early postoperative complications in patients undergoing low anterior resection (LAR) for rectal cancer.
methodsThis retrospective study included adult patients who underwent LAR for rectal cancer between January 1, 2018 and December 31, 2024. The patients were divided into two groups, those with and those without early postoperative complications. Complications developing within the first 30 days after LAR were considered early and complications developing after 30 days were considered late. The level of statistical significance in all statistical evaluations was set as
resultsA total of 105 patients underwent LAR for rectal cancer, comprising 66 (62.9%) males and 39 (37.1%) females with a mean age of 66 ± 12 years (28-85 years). Protective loop ileostomy was performed in 23 (21.9%) patients. The LAR was performed as open surgery in 63 (60%) patients and laparoscopically in 42 (40%) patients. The mean follow-up period was 46.44 ± 25 months (1-85 months) and the mean disease-free survival duration was 42.49 ± 24 months (1-85 months). Early postoperative complications were observed in 29 (27.6%) patients and late complications were observed in 14 (13.3%) patients. The most frequently seen early postoperative complication was anastomosis leakage in 10 (9.5%) patients. Advanced age, the presence of diabetes mellitus, advanced stage disease, increased preoperative eosinophil/lymphocyte ratio (ELR), and low preoperative albumin and hemoglobin levels were found to be significantly associated with early postoperative complications (
conclusionElevated preoperative ELR in patients undergoing LAR for rectal cancer may predict the development of early postoperative complications. Therefore, further studies are required to be able to establish the importance of the preoperative ELR.
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