ArticleWorld journal of gastrointestinal surgery2026
Diagnostic value of interleukin-8 in colon cancer: Prospective, case-control study.
Article in World journal of gastrointestinal surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Interleukin-8 in health and disease.Molecular biomedicine · 2026Review
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4 authors.
Funding
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Abstract
backgroundInterleukin-8 (IL-8), a pro-inflammatory chemokine, is implicated in angiogenesis, tumor growth, and metastasis. However, its diagnostic and prognostic significance in colorectal cancer remains unclear.
aimTo evaluate the diagnostic utility of serum IL-8 in patients with newly diagnosed colon adenocarcinoma.
methodsIn this prospective case-control study, 44 treatment-naïve patients with colon adenocarcinoma and 44 age-matched healthy controls were enrolled. Preoperative serum IL-8 levels were measured by enzyme-linked immunosorbent assay. Statistical analyses included univariate and multivariate models, odds ratios, and receiver operating characteristic (ROC) curve analysis.
resultsSerum IL-8 levels were significantly higher in patients than in controls (
conclusionIL-8 may serve as a diagnostic biomarker in colon adenocarcinoma, and its potential prognostic role warrants validation in larger, multicenter cohorts.
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