ArticleJournal of oral and maxillofacial pathology : JOMFP2025
Oral T-cell Non-Hodgkin's lymphoma in an HIV-positive patient: A rare case emphasizing the diagnostic value of immunohistochemistry.
Article in Journal of oral and maxillofacial pathology : JOMFP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
T-cell non-Hodgkin's lymphoma (NHL) is a rare and aggressive malignancy with unusual oral manifestations. Its clinical diagnosis can be particularly challenging in HIV-positive individuals due to overlapping features with other HIV-associated lesions, such as Kaposi sarcoma or necrotizing periodontal conditions. We report a case of a 38-year-old HIV-positive man presenting with a rapidly enlarging mass in the left posterior maxilla. Clinical and radiographic findings were nonspecific, necessitating histopathological and immunohistochemical evaluation. Immunohistochemical analyses confirmed the diagnosis of T-cell NHL. This case highlights the importance of immunohistochemistry in accurately diagnosing atypical oral lesions, especially in immunocompromised individuals.
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