ArticleJournal of oral and maxillofacial pathology : JOMFP2025
Heterogeneity of HPV genotypes in oropharyngeal condyloma accuminatum: Case report from Ecuador.
Article in Journal of oral and maxillofacial pathology : JOMFP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Acuminated condyloma (AC), or venereal wart, is a viral infection caused by the human papillomavirus (HPV), primarily transmitted through sexual contact. Adolescents and young adults are the most vulnerable groups. Its presentation in the oral cavity is atypical, as is the involvement of HPV genotypes other than HPV-6/11/16/18. This report describes an unusual case of oropharyngeal condyloma in a young adult woman with dyslipidaemia and vitamin D deficiency, which exhibited co-infection with low-risk (HPV-6, 11) and high-risk oncogenic genotypes (HPV-59, 82). The latter two genotypes have not been reported in oral or oropharyngeal AC cases so far. Diagnosis was based on clinical and pathological findings, with a favourable prognosis despite the lesion's location. While AC diagnosis is primarily clinical, histopathological analysis is crucial for distinguishing it from other HPV-related oral conditions. Genotyping, though not essential for diagnosis, has epidemiological relevance in guiding vaccination strategies.
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