ArticleJournal of oral and maxillofacial pathology : JOMFP2025
Brown tumor of mandible: A conundrum towards the diagnosis.
Article in Journal of oral and maxillofacial pathology : JOMFP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Brown Tumor is a rare, reactive, giant cell associated, late-stage bone lesion occuring as a result of long term untreated primary or secondary hyperparathyroidism (HPT). It clinically manifests as a high turnover bone disease, which typically shows increased parathyroid hormone (PTH) secretion in response to low serum calcium concentration thereby enhancing calcium reabsorption and osteoclastic bone resorption, hence called osteoclastoma or giant cell reparative granuloma or osteitis fibrosa cystica. Brown tumor associated with HPT can be seen in any part of the human skeleton, However clinically significant lesion involving the craniofacial skeleton is quite rare. Here we report a rare case of Brown tumor associated with HPT in a 28 year old female involving the right side of mandible.
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