ReviewFood science and biotechnology2026
Navigating the challenges in fucoidan industrialization: factors affecting biological activity and strategies for application of functional material.
Review in Food science and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Fucoidan and alginate from brown seaweeds: extraction, structural diversity, biocompatibility, biodegradability, and biomedical applications.Frontiers in plant science · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fucoidan, a sulfated polysaccharide from brown seaweed, exhibits diverse biological activities such as anti-inflammatory, antiviral, anticoagulant, and anticancer effects. However, its structural attributes, influenced by seaweed species, environment, and extraction methods, pose challenges for standardization and industrial application. Issues such as composition variability, regulatory concerns, and high production costs further hinder commercialization. We aimed to provide an integrated analysis of fucoidan, spanning its structural characterization, biological activities, and challenges in industrial applications, while proposing strategies to enhance its utilization. In this review, we synthesized the literature on advanced extraction, purification, and bioavailability enhancement techniques to address key challenges in fucoidan research and industrialization. Critical factors influencing fucoidan's structure and bioactivity were identified. Advanced methods improved extraction yields and reduced contaminants, addressing industrial barriers. This review offers valuable insights into the current state of fucoidan research and its prospects in the functional materials of dietary supplements, pharmaceuticals, nutraceuticals, and cosmetics. Graphical abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s10068-025-01937-5.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.