Evidence map›Paper›PMID 41695760›Full record

ArticleBlood vessels, thrombosis & hemostasis2026

A novel palmitoylethanolamide formulation improves hyperalgesia and red cell instability in murine sickle cell disease.

Donovan A Argueta, Natalie R Garcia, Alex Mabou Tagne, Daniele Piomelli, Kalpna Gupta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood vessels, thrombosis & hemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Donovan A ArguetaDivision of Hematology/Oncology, Department of Medicine, University of California, Irvine, Irvine, CA.
Natalie R GarciaDivision of Hematology/Oncology, Department of Medicine, University of California, Irvine, Irvine, CA.
Alex Mabou TagneDepartment of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, Irvine, CA.
Daniele PiomelliDepartment of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, Irvine, CA.
Kalpna GuptaDivision of Hematology/Oncology, Department of Medicine, University of California, Irvine, Irvine, CA.

Funding

Targeting p38/JNK MAPK to ameliorate cisplatin-induced adverse sequelae on the nervous systemR01CA263806 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI BOTA, DANIELA ANNENELIE, GUPTA, KALPNA · 2021 to 2025
$3.4M
Targeting mechanisms contributing to vascular dysfunction and pain in sickle cell diseaseR01HL147562 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GUPTA, KALPNA · 2019 to 2022
$3.4M
Sickle Cell Disease Pain Analgesia And Integrative NetworkU24AT012868 · NCCIH · UNIVERSITY OF CALIFORNIA-IRVINE · PI Claudia Michelle Campbell, Kalpna Gupta · 2024 to 2026
$2.8M
Nutrition-based interventions to ameliorate pain in sickle cell diseaseK99AT012494 · NCCIH · UNIVERSITY OF CALIFORNIA-IRVINE · PI ARGUETA, DONOVAN ALEXANDER · 2024 to 2025
$241k
NCCIH NIH HHS K99 AT012494NCCIH NIH HHS U24 AT012868NCI NIH HHS R01 CA263806NHLBI NIH HHS R01 HL147562
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41695760
PMCPMC12905986

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.