ArticleWorld journal of orthopedics2026
Impact of preoperative frailty on complications, readmissions, and functional recovery following total knee arthroplasty in elderly patients.
Article in World journal of orthopedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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8 authors.
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Abstract
backgroundTotal knee arthroplasty (TKA) is increasingly performed in elderly patients with osteoarthritis, yet preoperative frailty is associated with adverse outcomes. Limited data exist from South Asian regions like Pakistan, where resource constraints and high osteoarthritis prevalence may influence these associations.
aimTo evaluate the association between preoperative frailty, assessed by the modified Frailty Index, and postoperative complications, hospital length of stay (LOS), 90-day readmission rates, and 1-year functional recovery in elderly Pakistani patients undergoing primary TKA.
methodsThis retrospective cohort study analyzed de-identified records from Bahawal Victoria Hospital, Bahawalpur, Pakistan (from January 2015 to September 2025). Patients aged ≥ 65 years with primary unilateral TKA for osteoarthritis were included. Frail patients (
resultsPost-matching, groups were balanced. Frail patients had higher composite complications [21.1%
conclusionPreoperative frailty is associated with increased complications, extended LOS, higher readmissions, and impaired functional recovery in elderly TKA patients in this Pakistani cohort. These findings are most directly applicable to tertiary care centers in Pakistan with comparable patient complexity and resource availability. Extrapolation to primary care or markedly different healthcare systems requires further validation. Routine frailty screening may aid risk stratification and perioperative management in similar settings, considering regional challenges such as high tuberculosis prevalence.
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