Evidence map›Paper›PMID 41695735›Full record

ArticleWorld journal of orthopedics2026

Value of "true" leukocytosis formula in determining total knee arthroplasty prosthetic joint infection in the community hospital setting.

Brendan M Sweeney, Shaan Sadhwani, Timothy Edwards, Matthew Kelly

Abstract read
In one paragraph

Article in World journal of orthopedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Brendan M SweeneyDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center of Central PA, Harrisburg, PA 17109, United States. sweeneybm4@upmc.edu.
Shaan SadhwaniDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center of Central PA, Harrisburg, PA 17109, United States.
Timothy EdwardsDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center of Central PA, Harrisburg, PA 17109, United States.
Matthew KellyDepartment of Orthopedic Surgery, Orthopedic Institute of PA, Harrisburg, PA 17109, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the advent of recent point of care testing to evaluate for prosthetic joint infection (PJI) such as alpha-defensin and calprotectin, the diagnosis of PJI has reached a new paramount. The most widely accepted diagnostic criteria in the literature at this time is the international consensus meeting (ICM) score by Parvizi

aimTo determine if the "true leukocytosis" formula for prosthetic joint aspirations is useful in determining PJIs.

methodsOf 158 cases with International Classification of Diseases, 10

resultsOf 81 cases met the inclusion criteria and had preoperative ICM scores calculated. Of the 81 cases that met inclusion criteria, no cases were found to have different preoperative ICM scores after applying the correction formula for "true leukocytosis" proposed by Ghanem

conclusionGiven the lack of variance in ICM score following the proposed correction formula, it appears that the proposed "true leukocytosis" formula is not a useful adjuvant in treatment decision making.

Indexed as

CriteriaInternational consensus meeting criteriaPeriprosthetic joint infectionTotal knee arthroplastyTotal nucleated cell countTrue leukocytosis

Identifiers

PMID41695735
PMCPMC12898235

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