ArticleWorld journal of orthopedics2026
Effect of teriparatide on improving fracture union in osteoporotic intertrochanteric fractures: A systematic review and meta-analysis.
Article in World journal of orthopedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Effect of teriparatide on improving fracture union in osteoporotic intertrochanteric fractures: A systematic review and meta-analysis.World journal of orthopedics · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntertrochanteric or pertrochanteric fractures are common among the elderly population. They are primarily treated by internal fixation. Malunion, delayed union, and implant-related complications are often seen in this population due to osteoporosis, which leads to inadequate bone stock and delayed healing of bone. Teriparatide is an established first-line anabolic treatment for osteoporosis that increases bone turnover and promotes new bone formation. Recent papers have shown its role in fracture union in which it enhanced the callus formation and bridged the fractured ends of the bones.
aimTo determine the effect of subcutaneous injection of teriparatide on osteoporotic intertrochanteric fractures.
methodsWe searched PubMed, EMBASE, Scopus, and Cochrane Library for English language articles that were published by June 3, 2025. We selected articles that compared the use of teriparatide injection with either no injection or placebo in patients with osteoporosis who experienced an intertrochanteric fracture that was treated with internal fixation. Relevant data, including union time (primary outcome variable) and other radiological and functional outcome parameters, were extracted from the included studies. The web version of Cochrane's Review Manager was used for meta-analysis.
resultsSix studies (four randomized controlled trials and two non-randomized studies) met the inclusion criteria for this systematic review. A total of 393 patients [teriparatide (
conclusionThe meta-analysis showed that teriparatide reduced union time, varus collapse, and complications in osteoporotic intertrochanteric fractures. However, these findings should be interpreted cautiously due to limited evidence and small sample size.
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