Evidence map›Paper›PMID 41695695›Full record

ArticlePeerJ2026

A retrospective metatranscriptomic study of respiratory pathogens causing adult community-acquired pneumonia in Wuxi, China, before the pandemic.

Yan-Jun Kang, Juan Liu, Yumeng Gao, Yujun Chen, Yan Wang, Chao Shi, Yuan Shen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yan-Jun Kang *Affiliated Children's Hospital of Jiangnan University, Wuxi, China.
Juan Liu *Wuxi Center for Disease Control and Prevention, Wuxi, China.
Yumeng GaoWuxi Center for Disease Control and Prevention, Wuxi, China.
Yujun ChenWuxi Center for Disease Control and Prevention, Wuxi, China.
Yan WangWuxi Center for Disease Control and Prevention, Wuxi, China.
Chao ShiWuxi Center for Disease Control and Prevention, Wuxi, China.
Yuan ShenWuxi Center for Disease Control and Prevention, Wuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has substantially altered respiratory pathogen circulation, underscoring the critical need for pre-pandemic baseline data to interpret current epidemiological trends. To establish this baseline, we employed metatranscriptomic sequencing to characterize the etiology of community-acquired pneumonia (CAP) in 20 adult patients hospitalized in Wuxi, China, during 2018-2019. Following ribosomal RNA depletion, sequencing data were analyzed using a stringent dual-filter strategy (RPM ≥ 100 and Z-score ≥ 2) to identify high-confidence pathogens. Our analysis revealed a complex, polymicrobial landscape. Bacterial pathogens predominated, with

Indexed as

Community-Acquired PneumoniaAdultAgedChinaCoinfectionCommunity-Acquired InfectionsCOVID-19FemaleHumansMaleMiddle AgedPhylogenyRetrospective StudiesSARS-CoV-2TranscriptomeCommunity-acquired pneumonia (CAP)Metatranscriptomic sequencingMicrobial diversityPre-pandemic baselineRespiratory pathogens

Identifiers

PMID41695695
PMCPMC12903900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.