Evidence map›Paper›PMID 41695539›Full record

ArticleFrontiers in plant science2025

Gene expression and evolution of Bowman-Birk protease inhibitors in wild and domesticated

Elisa Toini, Maria Totaro, Giuseppe Silvestri, Jacopo Vertemara, Giovanni Zecca, Davide Panzeri, Emily Rose Palm, Robert Philipp Wagensommer, Giuseppe Zampella, Massimo Labra and 1 more

Abstract read
In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elisa ToiniDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.
Maria TotaroDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.
Giuseppe SilvestriDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.
Jacopo VertemaraDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.
Giovanni ZeccaDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.
Davide PanzeriDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.
Emily Rose PalmDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.
Robert Philipp WagensommerFaculty of Education, Free University of Bozen-Bolzano, Bolzano, Italy.
Giuseppe ZampellaDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.
Massimo LabraDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.
Fabrizio GrassiDepartment of Biotechnology and Bioscience, University of Milan-Bicocca, Milano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bowman-Birk protease inhibitors (BBIs) are multifunctional proteins with a double-headed structure, featuring two distinct inhibitory loops that target trypsin and chymotrypsin proteases. BBI regulates protease activity in plants and provides defense against pests and pathogens, but little is still known about their expression levels and their ability to interact with natural targets. Our results showed that

Indexed as

binding energybioprospectingBowman-Birk protease inhibitorsFabaceaegene diversityVigna

Identifiers

PMID41695539
PMCPMC12894363

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.