Evidence map›Paper›PMID 41695510›Full record

ArticleHeart rhythm O22026

Body surface potential mapping of ventricular depolarization and repolarization in phospholamban and plakophilin-2 cardiomyopathy.

Iris van der Schaaf, Manon Kloosterman, Machteld J Boonstra, Rob W Roudijk, Anneline S J M Te Riele, Peter M van Dam, Peter Loh

Abstract read
In one paragraph

Article in Heart rhythm O2, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Iris van der SchaafDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Manon KloostermanDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Machteld J BoonstraDepartment of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Rob W RoudijkDepartment of Cardiology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands.
Anneline S J M Te RieleDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Peter M van DamDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Peter LohDepartment of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pathogenic variants in plakophilin Objective: This study aimed to determine abnormalities in R-, S-, and T-wave amplitudes in Methods: 67 lead BSPM was performed in controls and Results: 152 subjects (40 [27;54] years; 51% women) (40 controls and 112 carriers [53 Conclusion: BSPM detected abnormal amplitudes within and beyond the 12-lead electrocardiogram, even in presymptomatic carriers. Follow-up BSPM suggests that these abnormalities are associated with disease progression, highlighting the potential benefit of BSPM in early disease detection.

Indexed as

Arrhythmogenic cardiomyopathyBody surface potential mappingCardiac depolarization and repolarizationElectrocardiogramR-, S-, and T-wave amplitudes

Identifiers

PMID41695510
PMCPMC12902137

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.