In-hospital outcomes of catheter ablation for ventricular tachycardia in patients with prior coronary artery bypass grafting.

Background: Catheter ablation is an established therapy for recurrent ventricular tachycardia (VT). However, outcomes in patients with prior coronary artery bypass grafting (CABG) remain poorly defined. Objective: This study aimed to evaluate in-hospital outcomes following VT ablation in patients with and without a history of CABG. Methods: We used the National Inpatient Sample database (2008-2022) to identify adults with a primary diagnosis of VT who underwent ablation. Patients were stratified by prior CABG status. Propensity score weighting (PSW) was applied to adjust for baseline characteristics. The primary outcome was in-hospital mortality. Secondary outcomes included procedural complications and measures of health care utilization. A subgroup analysis was performed for patients with coronary artery disease (CAD). Results: Among 35,860 patients undergoing VT ablation, 18.2% had a history of CABG. After PSW, in-hospital mortality was similar between CABG and non-CABG groups (2.0% vs 2.3%, Conclusion: In this national cohort, prior CABG was not associated with increased in-hospital mortality or major complications after VT ablation. Patients who underwent CABG experienced higher rates of AMI and cardiac arrest but fewer pericardial complications. In a CAD- subgroup, the AMI association was attenuated and trended in the same direction.