Evidence map›Paper›PMID 41695489›Full record

ArticleTheranostics2026

Use of Dual-Modality Antibody Imaging for Assessment of Lymph Node Metastases in Head and Neck Cancer.

Nicole Meeks, Ashtyn G McAdoo, Yu-Jin Lee, Ramsha Akhund, Gary Smith, Jared Grice, Joseph Hoang, Kurt R Zinn, Marisa E Hom, Michael C Topf and 2 more

Abstract read
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Automated cGMP Radiosynthesis of [Molecular imaging and biology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nicole MeeksDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Ashtyn G McAdooDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Yu-Jin LeeDepartment of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Ramsha AkhundDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Gary SmithVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
Jared GriceDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Joseph HoangDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA.
Kurt R ZinnDepartment of Radiology, Michigan State University College of Human Medicine, East Lansing, MI, USA.
Marisa E HomDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Michael C TopfDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Adam J RosenbergVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
Eben L RosenthalDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8M
Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
Targeted Dual Modality Imaging for Detection and Removal of Head and Neck CancerR01CA266233 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI EBEN L. ROSENTHAL · 2022 to 2026
$2.1M
Secondary Molecular Imaging (SMI) for head and neck cancerR01CA279249 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI EBEN L. ROSENTHAL · 2024 to 2026
$1.1M
Augmented Reality to Guide Head and Neck Cancer SurgeryK08CA293255 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Michael Topf · 2024 to 2026
$645k
cGMP Compliant HPLC for Radiopharmaceutical Quality ControlS10OD032383 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PETERSON, TODD E · 2022 to 2022
$91k
NCI NIH HHS K08 CA293255NCI NIH HHS K12 CA090625NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA266233NCI NIH HHS R01 CA279249NIH HHS S10 OD032383
6 · The paper itself

Abstract

Surgical management of head and neck squamous cell carcinoma (HNSCC) patients often requires resection of the deep cervical lymph nodes. Fluorescence guided surgery (FGS) is a growing area of oncologic surgery that has shown promise for this purpose, however, it is limited by the signal penetration through the neck. To address this, we sought to evaluate the efficacy of the anti-EGFR antibody [

Indexed as

Head and Neck NeoplasmsLymphatic MetastasisOptical ImagingPanitumumabAgedBenzenesulfonatesFemaleHumansIndium RadioisotopesIndolesLymph NodesMaleMiddle AgedSingle Photon Emission Computed Tomography Computed TomographyBenzenesulfonatesIndium RadioisotopesIndolesIRDye 800CWPanitumumabdual-modalityfluorescence guided surgeryhead and neck cancerintraoperative detectionradioguided surgery

Identifiers

PMID41695489
PMCPMC12905667

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.