Evidence map›Paper›PMID 41695441›Full record

ArticleThe Pan African medical journal2025

A hidden site: positron emission tomography-computed tomography (PET-CT) unveiling subclinical masseter involvement in follicular lymphoma - case report.

Sana Ferchichi, Hamida Khémiri Guerbouj, Zahra Jouini, Ghada Kharrat, Wafa Skouri, Haifa Tounsi, Raja Amri

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sana FerchichiDepartment of Otorhinolaryngology, Ear and Head and Neck (ENT) Surgery, Taher Maâmouri Hospital, Nabeul, Tunisia.
Hamida Khémiri GuerboujDepartment of Internal Medicine, Taher Maâmouri Hospital, Nabeul, Tunisia.
Zahra JouiniDepartment of Otorhinolaryngology, Ear and Head and Neck (ENT) Surgery, Taher Maâmouri Hospital, Nabeul, Tunisia.
Ghada KharratDepartment of Otorhinolaryngology, Ear and Head and Neck (ENT) Surgery, Taher Maâmouri Hospital, Nabeul, Tunisia.
Wafa SkouriDepartment of Internal Medicine, Taher Maâmouri Hospital, Nabeul, Tunisia.
Haifa TounsiDepartment of Internal Medicine, Taher Maâmouri Hospital, Nabeul, Tunisia.
Raja AmriDepartment of Internal Medicine, Taher Maâmouri Hospital, Nabeul, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extranodal lymphoma involvement refers to lymphoma arising outside primary lymphatic organs. Muscular involvement is rare. This case report highlights the critical role of positron emission tomography-computed tomography (PET-CT) in detecting underestimated extranodal lesions, especially in muscles. We report the case of a 66-year-old patient with no prior significant medical history who presented with 3 months of cervical lymphadenopathy, asthenia, and night sweats. Examination revealed supracentimetric elastic cervical and inguinal lymphadenopathy and splenomegaly. Computed tomography suggested nodal disease above and below the diaphragm. Biopsy confirmed grade 3B follicular lymphoma and bone marrow infiltration. Positron emission tomography-computed tomography revealed intense fluorodeoxyglucose (FDG) uptake in nodal regions, spleen, bone marrow, and left masseter muscle, which was not visible on CT. The disease was staged as Ann Arbor stage IV, and the patient was planned for 8 cycles of R-CHOP and intrathecal methotrexate. As a final point,

Indexed as

Lymphoma, FollicularMasseter MusclePositron Emission Tomography Computed TomographyAgedAntineoplastic Combined Chemotherapy ProtocolsBiopsyCyclophosphamideDoxorubicinFluorodeoxyglucose F18HumansMaleMethotrexateNeoplasm StagingPrednisoneRadiopharmaceuticalsRituximabCyclophosphamideDoxorubicinFluorodeoxyglucose F18MethotrexatePrednisoneRadiopharmaceuticalsR-CHOP protocolRituximabVincristinecase reportextranodal diseaseLymphomamuscle involvementpositron emission tomography

Identifiers

PMID41695441
PMCPMC12904760

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.