ArticleVeterinary medicine international2026
Cytomolecular and In Vitro Toxicity Studies on Bisphenol A Effect on Ovine Granulosa Cells.
Article in Veterinary medicine international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Bisphenols and follicle function in farm species.The Journal of reproduction and development · 2026Review
- Cytomolecular and In Vitro Toxicity Studies on Bisphenol A Effect on Ovine Granulosa Cells.Veterinary medicine international · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bisphenol A (BPA), an organic environment chemical, has extensive presence in consumer goods and food/feed items. The present study aimed to explore how BPA influenced the viability, proliferation, apoptosis, and steroidogenic activity of ovine ovarian granulosa cells (GCs). GCs were isolated from ovine ovaries obtained from a local abattoir and were cultured for 2, 3, and 6 days in the presence of varying BPA concentrations (0, 1, 10, 25, 50, and 100 μm). The proliferation and cytotoxicity of the GCs were evaluated using kit assays, and the 72-h culture's spent media were pooled to measure the hormone concentrations. qPCR was performed for the study of gene expression-related apoptosis and steroidogenesis. For further confirmation of viability and apoptosis, the trypan blue exclusion test and Hoechst staining were performed. The findings revealed that the metabolic activity was significantly reduced at 50 μm, while the cell viability dropped notably (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.