SynthesisWorld journal of gastroenterology2026
Effects of bariatric surgery on obesity associated gastroesophageal reflux disease: Insights from a systematic review and network meta-analysis.
Synthesis in World journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundObesity is a global epidemic frequently associated with gastroesophageal reflux disease (GERD). Metabolic and bariatric surgery (MBS) is the most effective treatment for weight reduction in patients with obesity, with the most commonly performed procedures being sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one-anastomosis gastric bypass (OAGB). Many recent studies focused on determining the best procedure for patients with obesity and GERD; however, results from these studies vary, and the optimal procedure remains uncertain.
aimTo compare the effects of MBSs - SG, RYGB, and OAGB - and their combinations with antireflux procedures on weight loss and GERD outcomes.
methodsA systematic search was performed to identify randomized controlled trials evaluating MBS in patients with obesity and GERD. A network meta-analysis was conducted to estimate the relative effectiveness of different procedures on body mass index reduction, percent excess weight loss, GERD remission, GERD onset, postoperative proton pump inhibitor use, esophagitis, and complication rates.
resultsSixteen randomized controlled trials including SG, RYGB, OAGB and their combined procedures (
conclusionRYGB and OAGB were more effective than SG in patients with obesity and GERD, and addition of antireflux procedures to MBS did not improve GERD outcome.
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