Evidence map›Paper›PMID 41695193›Full record

ArticleJHLT open2026

Frailty assessment and candidate optimization before cardiothoracic transplantation.

Antoine Premachandra, Jacob Klapper, Jonathan Messika, Maira Gaillard, Martin Kloeckner, Kamrouz Ghadimi, Matthieu Reffienna, Krista Ingle, Kirti Magudia, Brandi Bottiger

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Antoine PremachandraDepartment of Anesthesiology, Foch Hospital, Suresnes, France.
Jacob KlapperDivision of Cardiothoracic Surgery, Department of Surgery, Duke Hospital, Durham, NC.
Jonathan MessikaThoracic Intensive Care Unit, Lung Surgery and Transplantation, Foch Hospital, Suresnes, France.
Maira GaillardDepartment of Cardiac Surgery, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Martin KloecknerDepartment of Cardiology, Marie Lannelongue Hospital, Le Plessis-Robinson, France.
Kamrouz GhadimiCardiothoracic Anesthesiology and Critical Care Medicine Divisions, Department of Anesthesiology, Duke Hospital, Durham, NC.
Matthieu ReffiennaDepartment of Physical Therapy, Foch Hospital, Suresnes, France.
Krista IngleDepartment of Psychiatry and Behavioral Sciences, Duke Hospital, Durham, NC.
Kirti MagudiaDepartment of Radiology, Duke Hospital, Durham, NC.
Brandi BottigerCardiothoracic Anesthesiology and Critical Care Medicine Divisions, Department of Anesthesiology, Duke Hospital, Durham, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frailty is an important syndrome in an aging thoracic transplant population, particularly in the context of end-stage cardiopulmonary disease. In this review, we discuss the core problem of lack of physiologic reserve in these patients and its relationship to perioperative outcomes, how to define and measure frailty in the context of heart and lung transplant and identify interventions to treat contributors to this clinical syndrome. We highlight the critical need in the transplant community to identify and treat these conditions prior to their transplantation and to prevent comorbidity and mortality.

Indexed as

BiomarkersCachexiaFrailtyHeart transplantationLung transplantationPrehabilitationSarcopenia

Identifiers

PMID41695193
PMCPMC12906103

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.