Evidence map›Paper›PMID 41695075›Full record

ArticleJPGN reports2026

Isolated gastrointestinal Langerhans cell histiocytosis in a 16-month-old child: A case report.

Al-Qasim Al-Bahlani, Laraib Touseeq, Mohammed Al-Masqari, Emad Saad

Abstract read
In one paragraph

Article in JPGN reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Al-Qasim Al-BahlaniDepartment of Child Health, Pediatric Gastroenterology and Hepatology Section Royal Hospital Muscat Sultanate of Oman.ORCID https://orcid.org/0000-0002-6040-4977
Laraib TouseeqDepartment of Child Health, Pediatric Gastroenterology and Hepatology Section Royal Hospital Muscat Sultanate of Oman.
Mohammed Al-MasqariHistopathology Department Royal Hospital Muscat Sultanate of Oman.
Emad SaadNational Oncology Centre Royal Hospital Muscat Sultanate of Oman.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by clonal proliferation of Langerhans cells, most often involving the skin or bone. Isolated gastrointestinal (GI) involvement is extremely uncommon in young children. We report a 16-month-old girl with a 1-month history of chronic vomiting, bloody diarrhea, and failure to thrive who was found to have GI-LCH without systemic involvement. She was started on standard LCH chemotherapy with a favorable clinical response. This case highlights the importance of considering LCH in infants/toddlers with unexplained GI symptoms and the utility of targeted molecular testing (e.g., BRAF mutation analysis) in guiding therapy.

Indexed as

BRAF mutationchronic diarrheahistological diagnosisrare pediatric gastrointestinal disease

Identifiers

PMID41695075
PMCPMC12894071

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.