Evidence map›Paper›PMID 41695062›Full record

ArticleJPGN reports2026

Muscular and serosal eosinophilic gastritis and enteritis with eosinophilic ascites successfully treated with dupilumab.

Almudena Sánchez-Ramírez, Alejandro García-Díaz, Ruth García-Martínez de Bartolomé, Maria Isabel García-Hidalgo, Maria Luz Cilleruelo, Enriqueta Román-Riechmann, Carolina Gutiérrez-Junquera

Abstract read
In one paragraph

Article in JPGN reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Almudena Sánchez-RamírezPediatric Gastroenterology Unit Hospital Universitario Puerta de Hierro Majadahonda Madrid Spain.
Alejandro García-DíazPediatric Gastroenterology Unit Hospital Universitario Puerta de Hierro Majadahonda Madrid Spain.ORCID https://orcid.org/0009-0007-8363-4760
Ruth García-Martínez de BartoloméDepartment of Pediatrics EAP Valle de la Oliva Madrid Spain.
Maria Isabel García-HidalgoDepartment of Radiology Hospital Universitario Puerta de Hierro Majadahonda Madrid Spain.
Maria Luz CillerueloPediatric Gastroenterology Unit Hospital Universitario Puerta de Hierro Majadahonda Madrid Spain.
Enriqueta Román-RiechmannPediatric Gastroenterology Unit Hospital Universitario Puerta de Hierro Majadahonda Madrid Spain.
Carolina Gutiérrez-JunqueraPediatric Gastroenterology Unit Hospital Universitario Puerta de Hierro Majadahonda Madrid Spain.ORCID https://orcid.org/0000-0003-0313-7072

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary eosinophilic gastrointestinal disorders beyond the esophagus (EGIDs) are rare, predominantly Th2-mediated inflammatory conditions, affecting various segments of the gastrointestinal tract. We report the case of a 12-year-old boy with recurrent abdominal pain, peripheral eosinophilia, and progressive gastritis, duodenitis, and enteritis with eosinophilic ascites. He was diagnosed with extensive EGID with muscular and serosal involvement. He was treated with oral corticosteroids and milk elimination diet, which provided temporary relief, but relapses prompted the addition of dupilumab, which achieved durable remission. To our knowledge, this is the first reported case demonstrating the effectiveness of this monoclonal antibody in EGIDs with serosal involvement and eosinophilic ascites. This case highlights the therapeutic potential of dupilumab in refractory EGID cases involving deeper gastrointestinal layers.

Indexed as

eosinophilic gastrointestinal disordersinterleukin 13 blockade, corticosteroids dependencyinterleukin‐4 blockade

Identifiers

PMID41695062
PMCPMC12894091

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.