Evidence map›Paper›PMID 41695052›Full record

ArticleJPGN reports2026

Expect the unexpected: A case of penetrating Crohn's disease complicated by foreign body ingestion.

Meredith R Kline, Baddr A Shakhsheer, Amelia Kellar

Abstract read
In one paragraph

Article in JPGN reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meredith R KlineThe University of Chicago Medicine Inflammatory Bowel Disease Center Chicago Illinois USA.ORCID https://orcid.org/0000-0003-4040-2066
Baddr A ShakhsheerSection of Pediatric Surgery, Department of Surgery University of Chicago Chicago Illinois USA.
Amelia KellarThe University of Chicago Medicine Inflammatory Bowel Disease Center Chicago Illinois USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 17-year-old nonverbal male with autism spectrum disorder (ASD) presented with abdominal pain, diarrhea, and weight loss. Initial workup revealed penetrating Crohn's disease (CD) with an ileosigmoid fistula and abscess. After initial improvement with antibiotics, enteral nutrition (EN), and infliximab (IFX), he developed recurrent abdominal pain and elevation of inflammatory markers. Repeat imaging suggested disease progression, prompting surgical intervention. During ileocecal resection and fistula takedown, a foreign body (the hand of an action figurine) was discovered, likely contributing to bowel obstruction and abscess recurrence. This case highlights the importance of medical and surgical comanagement of penetrating CD, as well as the need to maintain a broad differential diagnosis when new or worsening symptoms arise.

Indexed as

autism spectrum disorderileosigmoid fistula

Identifiers

PMID41695052
PMCPMC12894048

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.