Evidence map›Paper›PMID 41695049›Full record

ArticleJPGN reports2026

Subthreshold eosinophilia during food impaction may mask eosinophilic esophagitis: A pediatric case series.

Mark Mahon, Amanda Muir

Abstract read
In one paragraph

Article in JPGN reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mark MahonDivision of Gastroenterology, Hepatology, and Nutrition Children's Hospital of Philadelphia Philadelphia Pennsylvania USA.ORCID https://orcid.org/0000-0002-7548-7939
Amanda MuirDivision of Gastroenterology, Hepatology, and Nutrition Children's Hospital of Philadelphia Philadelphia Pennsylvania USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To describe the clinical scenario and need for longitudinal follow-up of pediatric patients presenting with esophageal food impactions (EFIs) regardless of esophageal biopsy eosinophil count. A retrospective chart review was conducted on patients with EFI who underwent endoscopic evaluation from August 2022 to August 2024. Patients demonstrating eosinophils per high-power field (HPF) between 1 and 14 were identified, and longitudinal assessment evaluated for potential eosinophilic esophagitis (EoE) diagnosis. Four patients presented with EFI and sub-diagnostic eosinophilic counts (1-14 eosinophils/HPF) were assessed longitudinally. In all cases, repeat endoscopy showed an increase in eosinophils, confirming EoE (eosinophils ≥ 15/HPF). EFI is a potential presenting sign of EoE, but initial biopsy results during EFI often show sub-diagnostic eosinophilic counts. Our findings underscore the need for adequate biopsy procurement at the time of EFI, longitudinal follow-up, and repeat endoscopy for accurate EoE diagnosis during EFI.

Indexed as

atopicdegranulateddysphagiaesophagusmucosa

Identifiers

PMID41695049
PMCPMC12894089

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.