ArticleHorticulture research2026
Molecular orchestration of malate and citrate metabolism: regulatory networks governing organic acid dynamics and fruit quality attributes.
Article in Horticulture research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Native Amazonian Inga Fruits as Sources of Bioactive Compounds withMolecules (Basel, Switzerland) · 2026Article
- Effects of Hot-Air Drying Temperature on Biochemical Quality, Drying Kinetics, and Predictive Modeling ofMolecules (Basel, Switzerland) · 2026Article
- Organ-Specific Distribution of Bioactive Compounds inAntioxidants (Basel, Switzerland) · 2026Article
- Metabolomic Profile of Aqueous Extracts of Commercial Samples of St John's Wort (International journal of molecular sciences · 2026Article
- Assessment of taste profile dynamics during crabapple (Frontiers in nutrition · 2026Article
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Authors and funding
2 authors.
Funding
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Abstract
In most fleshy fruit, malate and citrate represent the predominant organic acids, serving as key determinants of flavor and nutritional quality. Their concentrations undergo dynamic changes driven by complex biosynthetic pathways and multilayered genetic regulation. Beyond their impact on taste, these organic acids have pleiotropic effects, influencing secondary metabolism and postharvest performance. This review synthesizes current knowledge on the molecular mechanism governing malate and citrate metabolism, including genes responsible for biosynthesis, catabolism, and transport, as well as regulatory networks orchestrated by transcription factors, environmental factors, and phytohormones such as ethylene, abscisic acid (ABA), auxin, gibberellin (GA), and salicylic acid (SA) during fruit development and ripening. We also explored how the dynamics of citrate and malate interact with critical quality attributes, including starch metabolism, textural properties, and postharvest performance, while highlighting domestication-selected genes that influence acidity. Finally, we propose an integrative model delineates the multifactorial regulation of organic acid metabolism in fleshy fruits.
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Registered trials
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