Evidence map›Paper›PMID 41694949›Full record

ArticleCureus2026

Early Postmortem Changes in Pancreas: An Antemortem and Postmortem Computed Tomography Study.

Terumi Umeda, Shohei Inui, Satori Gonoi, Wataru Gonoi, Akira Katayama, Go Shirota, Kotaro Fujimoto, Hiroyuki Abe, Keisuke Nyunoya, Mariko Kurokawa and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Terumi UmedaRadiology, Shimane University, Izumo, JPN.
Shohei InuiRadiology, The University of Tokyo Graduate School of Medicine, Tokyo, JPN.
Satori GonoiRadiology, K. International School Tokyo (KIST), Tokyo, JPN.
Wataru GonoiRadiology, The University of Tokyo Graduate School of Medicine, Tokyo, JPN.
Akira KatayamaRadiology, The University of Tokyo Hospital, Tokyo, JPN.
Go ShirotaRadiology, The University of Tokyo Hospital, Tokyo, JPN.
Kotaro FujimotoRadiology, The University of Tokyo Hospital, Tokyo, JPN.
Hiroyuki AbePathology, The University of Tokyo Hospital, Tokyo, JPN.
Keisuke NyunoyaRadiology, The University of Tokyo Hospital, Tokyo, JPN.
Mariko KurokawaRadiology, The University of Tokyo Hospital, Tokyo, JPN.
Naomasa OkimotoRadiology, The University of Tokyo Hospital, Tokyo, JPN.
Masumi Takahashi-MizukiRadiology, The University of Tokyo Hospital, Tokyo, JPN.
Masanori IshidaRadiology, The University of Tokyo Hospital, Tokyo, JPN.
Tetsuo UshikuPathology, The University of Tokyo Graduate School of Medicine, Tokyo, JPN.
Osamu AbeRadiology, The University of Tokyo Graduate School of Medicine, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to investigate early postmortem changes of the healthy pancreas longitudinally across antemortem computed tomography (AMCT) to postmortem computed tomography (PMCT). MATERIALS AND

methodsThis study included adult patients who were treated and died at a university hospital and underwent unenhanced AMCT within seven months before death, and PMCT within 24 hours after death. Included subjects had undergone pathological autopsy between 2013 and 2020 and were proven to have a healthy pancreas on autopsy. The pancreatic parenchyma on images was segmented using CT-value threshold-assisted initial contouring followed by manual slice-by-slice refinement. Their volume, density, and histogram-based distribution parameters (skewness and kurtosis) of the voxel-wise pancreatic density distribution within the segmented pancreas region of interest were measured using an image analyzer on unenhanced AMCT and PMCT. The values were compared statistically.

resultsA total of 38 participants were included in the study (male/female, 23/15; mean age, 64.1±15.1 (SD) years). The pancreatic density on AMCT (31.2 ± 8.7 HU) decreased significantly on PMCT (26.6 ± 8.1 HU). Similarly, the pancreatic volume on AMCT (63.8 ± 23.2 ml) significantly reduced on PMCT (56.8 ± 22.6 ml). Histogram skewness of the voxel-wise pancreatic density distribution significantly increased from AMCT to PMCT, whereas histogram kurtosis of this density distribution exhibited a non-significant difference.

conclusionPancreatic density and volume significantly decrease in early postmortem. These findings provide a basis for interpreting normal postmortem pancreatic imaging.

Indexed as

computed tomographyforensic radiologypancreaspostmortem computed tomographypostmortem imaging

Identifiers

PMID41694949
PMCPMC12897900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.