Evidence map›Paper›PMID 41694712›Full record

ArticleMultifunctional materials2021

Bioinspired nanoantennas for opsin sensitization in optogenetic applications: a theoretical investigation.

Carl H C Keck, Nicholas J Rommelfanger, Zihao Ou, Guosong Hong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Multifunctional materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Red Light Optogenetics in Neuroscience.Frontiers in cellular neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carl H C KeckDepartment of Materials Science and Engineering, Stanford University, Stanford, CA 94305, United States of America.
Nicholas J RommelfangerDepartment of Applied Physics, Stanford University, Stanford, CA 94305, United States of America.
Zihao OuDepartment of Materials Science and Engineering, Stanford University, Stanford, CA 94305, United States of America.
Guosong HongDepartment of Materials Science and Engineering, Stanford University, Stanford, CA 94305, United States of America.ORCID 0000-0002-8858-4471

Funding

Brain Aging Studies with Single-Neuron Resolution Using Syringe-Injectable ElectronicsR00AG056636 · NIA · STANFORD UNIVERSITY · PI HONG, GUOSONG · 2018 to 2020
$745k
NIA NIH HHS R00 AG056636
6 · The paper itself

Abstract

Opsins with high sensitivity are desired to reduce dependence on optical fibers and enable deep-brain optogenetic stimulation through the intact scalp and skull, while minimizing brain tissue heating and the associated biasing of neural activity. While optimized opsin engineering has produced ultrasensitive and red-shifted opsins suitable for transcranial optogenetic stimulation, further improvements in sensitivity are throttled by biological limitations. Nanostructures are capable of generating near-field intensity enhancements of over 10

Indexed as

aluminum plasmonicsbioinspired materialsopsinsplasmonic enhancementtranscranial optogenetics

Identifiers

PMID41694712
PMCPMC12900125

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.