ArticleFrontiers in medical technology2026
Making the invisible visible: integrated visualization and automated quantification of thrombus deformation during mechanical thrombectomy.
Article in Frontiers in medical technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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Corrections and comments
- Erratum issued
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Abstract
Background: Mechanical thrombectomy using stent retrievers is a proven treatment for large vessel occlusion stroke, but quantitative and objective evaluation of device-thrombus interaction remains limited. Objective: This study introduces a novel algorithm and experimental framework to visualize and quantify thrombus deformation during retrieval under standardized Methods: An Results: In total, 36 and 47 thrombectomies were performed with the Embotrap III and NeVa, respectively. Both devices achieved high first-pass reperfusion rates (Embotrap III: 88.9%, NeVa: 87.2%). However, thrombus deformation (mean: 14.7 × 10 Conclusions: Our new imaging and analysis framework allows for objective, reproducible measurements of thrombus-stent interaction over time. Our findings support the high efficacy of both stent retrievers. While the Embotrap III exerted stronger mechanical deformation effects on the clots, initial distal thrombus migration occurred more often with the NeVa device. This approach may support more informed device selection and optimization of thrombectomy strategies to enhance reperfusion success and reduce distal embolization in acute ischemic stroke.
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