Evidence map›Paper›PMID 41694512›Full record

ArticleFrontiers in public health2026

Prevalence and trends in long-term survivors of early-onset vs. late-onset cancer: a serial cross-sectional study.

Qiang Yin, Run Xu, Dongmei Wang, Jian Li

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qiang YinDepartment of General Surgery, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, China.
Run XuDepartment of General Surgery, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, China.
Dongmei WangDepartment of General Surgery, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, China.
Jian LiDepartment of General Surgery, The Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With increasing global cancer survivorship, understanding differential trends by age at diagnosis is crucial for developing targeted care strategies. This study examines 27-year trends in early-onset (20-49 years) vs. late-onset (≥50 years) cancer survivorship in the US population. Methods: We analyzed nationally representative data from the National Health Interview Survey (1997-2023), identifying adults surviving ≥5 years post-diagnosis. Weighted prevalence estimates were calculated, and temporal trends were analyzed using Joinpoint regression to compute average annual percentage changes (AAPCs) with 95% confidence intervals (CIs). Results: Women represented 72.7% of early-onset cancer survivors, compared to 51.5% of late-onset cancer survivors. From 1997 to 2023, both prevalence of early-onset (AAPC 1.7, 95% CI: 1.4 to 2.0) and late-onset (AAPC 1.9, 95% CI: 1.7 to 2.1) cancer survivors increased significantly. The prevalence of male early-onset cancer survivors rose the most sharply (AAPC 3.1, 95% CI: 2.5 to 3.8), compared to prevalence of late-onset (AAPC 1.9, 95% CI: 1.6 to 2.3) or female cancer survivors (AAPC early-onset 1.3, 95% CI: 1.0 to 1.6; late-onset 1.7, 95% CI: 1.5 to 2.0). College-educated individuals had higher baseline prevalence and faster growth. Similarly, high-income groups showed elevated prevalence (early-onset 2.65%; late-onset 8.22%) and the most rapid increase was found in late-onset cancer survivors (AAPC 3.2, 95% CI: 2.5 to 3.9). Conclusion: These findings demonstrate universal increases in cancer survivorship with distinct socioeconomic and gender patterns, highlighting the need for tailored survivorship programs and targeted policies to address emerging disparities in long-term cancer care.

Indexed as

Age of OnsetCancer SurvivorsNeoplasmsAdultAgedCross-Sectional StudiesFemaleHealth SurveysHumansMaleMiddle AgedPrevalenceUnited StatesYoung Adultearly-onset cancerlate-onset cancerprevalencesurvivorshiptemporal trends

Identifiers

PMID41694512
PMCPMC12903913

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.