Evidence map›Paper›PMID 41694498›Full record

ArticleWorld journal of gastroenterology2026

Lack of follow-up in

Elisa Cantú-Germano, Leticia Moreira, Ángeles Pérez-Aisa, Samuel J Martínez-Domínguez, Irina Voynovan, Luis Bujanda, Laimas Jonaitis, Bojan Tepes, Ana Garre, Alfredo J Lucendo and 42 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

52 authors.

Elisa Cantú-GermanoDepartment of Gastroenterology, Hospital Clínic de Barcelona, Barcelona 08036, Catalonia, Spain.
Leticia MoreiraDepartment of Gastroenterology, Hospital Clínic de Barcelona, Barcelona 08036, Catalonia, Spain.
Ángeles Pérez-AisaDepartment of Gastroenterology, Hospital Universitario Costa del Sol, Red de Investigación en Cronicidad, Atención Primaria y Prevención y Promoción de la Salud (RICAPPS), Marbella 29603, Andalusia, Spain.
Samuel J Martínez-DomínguezEnfermedades Hepáticas y Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid 28029, Spain.
Irina VoynovanA.S. Loginov Moscow Clinical Scientific Center, Moskva, 111123, Russia.
Luis BujandaEnfermedades Hepáticas y Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid 28029, Spain.
Laimas JonaitisDepartment of Gastroenterology, Lithuanian University of Health Sciences, Kaunas 50161, Lithuania.
Bojan TepesDepartment of Gastroenterology, Diagnostic Center Rogaska, Rogaska Slatina 3250, Slovenia.
Ana GarreEnfermedades Hepáticas y Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid 28029, Spain.
Alfredo J LucendoEnfermedades Hepáticas y Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid 28029, Spain.
Frode LerangØstfold Hospital Trust, Grålum 1714, Norway.
Thomas ButlerTrinity Academic Gastroenterology Group, Clinical Medicine, Trinity College Dublin, Department of Gastroenterology, Tallaght University Hospital, Dublin D02 PN40, Ireland.
Umud MahmudovModern Hospital, Baku AZ1119, Azerbaijan.
Jose M HuguetDepartment of Gastroenterology, General University Hospital of Valencia, Valencia 46014, Spain.
Javier Tejedor-TejadaDepartment of Gastroenterology, Hospital Universitario de Cabueñes, Gijón 33394, Asturias, Spain.
Pavel BogomolovUniversal Clinic Private Medical Center, Moskva 109382, Russia.
Ian Lp BealesDepartment of Gastroenterology, Norwich Medical School, University of East Anglia, Norwich NR4 7UY, Norfolk, United Kingdom.
Perminder S PhullDepartment of Digestive Disorders, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, United Kingdom.
Manuel Pabon-CarrascoDepartment of Gastroenterology, Hospital Universitario Virgen de Valme, Sevilla 41014, Andalusia, Spain.
Manuel Castro-FernándezDepartment of Gastroenterology, Hospital Universitario Virgen de Valme, Sevilla 41014, Andalusia, Spain.
Sergey AlekseenkoDepartment of Hospital Therapy, Far Eastern State Medical University, Khabarovsk 680000, Russia.
Matteo PavoniDepartment of Medical and Surgical Sciences, Sant'Orsola-Malpighi University Hospital, Bologna 40138, Italy.
Oleg ZaytsevFirst Clinical Medical Centre, Kovrov 301910, Vladimirskaya Oblast, Russia.
Renate BumaneDepartment of Gastroenterology, Digestive Diseases Centre, Institute of Clinical and Preventive Medicine, University of Latvia, Riga LV1079, Latvia.
Maja DenkovskiInterni Oddelek, Diagnostic Centre, Bled 4620, Slovenia.
Manuel D CajalDepartment of Gastroenterology and Hepatology, Hospital Universitario San Jorge, Huesca 22004, Aragon, Spain.
Ilchishina TatianaDepartment of Gastroenterology, SM-clinic, Saint-Petersburg, Saint Petersburg 194355, Russia.
Miguel AreiaDepartment of Gastroenterology, Portuguese Oncology Institute of Coimbra (IPO Coimbra), RISE@CI-IPO (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Coimbra 3000-075, Portugal.
Alma Keco-HuergaDepartment of Gastroenterology, Hospital Universitario Virgen de Valme, Sevilla 41014, Andalusia, Spain.
Gülüstan BabayevaDepartment of Therapy, Azerbaijan State Advanced Training Institute for Doctors named after A. Aliyev, Baku 1072, Azerbaijan.
Fernando BermejoDepartment of Gastroenterology, University Hospital of Fuenlabrada, Fuenlabrada 28942, Spain.
Halis SimsekDepartment of Gastroenterology, Hacettepe University, Ankara 06690, Türkiye.
György M BuzásDepartment of Gastroenterology, Ferencváros Health Center, Budapest 1095, Hungary.
Giuseppe LosurdoDepartment of Gastroenterology, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari 70121, Puglia, Italy.
Dmitry S BordinDepartment of Pancreatic, Biliary and Upper Digestive Tract Disorders, A.S. Loginov Moscow Clinical Scientific Center, Department of Outpatient Therapy and Family Medicine, Tver State Medical University, Department of Propaedeutic of Internal Diseases and Gastroenterology, Russian University of Medicine, Moscow 111123, Russia.
Juozas KupcinskasDepartment of Gastroenterology, Lithuanian University of Health Sciences, Kaunas 50161, Lithuania.
Sinead M SmithSchool of Medicine, Trinity College, Dublin D02 PN40, Ireland.
Antonio GasbarriniDepartment of Internal Medicine and Gastroenterology, Fondazione Policlínico Universitario Agostino Gemelli IRCCS, Rome 00168, Italy.
Marcis LejaDepartment of Gastroenterology, Digestive Diseases Centre, Institute of Clinical and Preventive Medicine, University of Latvia, Riga LV1079, Latvia.
Ricardo Marcos-PintoDepartment of Gastroenterology, Centro Hospitalar do Porto, Universidade do Porto, Instituto De Ciências Biomédicas de Abel Salazar, Center for Research in Health Technologies and Information Systems (CINTESIS), Porto 4099-001, Portugal.
Cem SimsekDepartment of Gastroenterology, Hacettepe University, Mehmet Akif Inan, Health Sciences University, Medical Center, HC International Clinic, Ankara 06800, Türkiye.
Veronika PappDepartment of Surgery, Transplantation and Gastroenterology, Semmelweis University, Budapest 1085, Hungary.
Blas Jg RodríguezDepartment of Gastroenterology, Hospital Universitario Virgen Macarena, Sevilla 41013, Spain.
Pilar P MejideDepartment of Gastroenterology, Hospital de Cruces, Barakaldo 48903, Spain.
Ramón P VillarroyaDepartment of Gastroenterology, Hospital Universitario Infanta Sofía, Facultad de Medicina, Universidad Europea de Madrid, Madrid 28702, Spain.
Mónica S AlonsoDepartment of Gastroenterology, Hospital Universitario Santa Bárbara, Puertollano 13500, Castille-La Mancha, Spain.
Anna Cano-CatalàDepartment of Medicine, Gastrointestinal Oncology, Endoscopy and Surgery (GOES) research group, Althaia Xarxa Assistencial Universitària de Manresa, Institut de Recerca i Innovació en Ciències de la Vida i de la Salut de la Catalunya Central (IRIS-CC), Manresa 08243, Catalonia, Spain.
Francis MegraudINSERM U1312 BRIC, Université de Bordeaux, Bordeaeux 33076, France.
Colm O'MorainSchool of Medicine, Trinity College, Dublin D02 PN40, Ireland.
Pablo ParraEnfermedades Hepáticas y Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid 28029, Spain.
Olga P NyssenEnfermedades Hepáticas y Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid 28029, Spain.
Javier P GisbertEnfermedades Hepáticas y Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid 28029, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Maastricht VI/Florence consensus recommends the eradication of all

aimTo evaluate the reasons for and factors associated with non-retreatment after

methodsA multicenter, prospective registry (European registry on

resultsOf the 6904 patients with eradication failure, 950 (14%) were not retreated: 41% due to medical decisions, 50% due to patient decisions, and 9% due to other reasons. Frequent reasons for non-retreatment included previous poor tolerance, noncompliance, unclear indications, and multiple eradication attempts. From a medical perspective, non-retreatment was associated with age ≥ 71 years [odds ratio (OR) = 1.49; 95% confidence interval (CI): 1.04-2.13], previous noncompliance (OR = 4.27; 95%CI: 2.64-6.93), treatment discontinuation due to adverse events (OR = 2.06; 95%CI: 1.19-3.56), and number of previous attempts (OR range: 2.07-9.25). From the patient perspective, the associated factors included male sex (OR = 1.34; 95%CI: 1.10-1.63), two to four previous eradication attempts (OR range: 1.69-3.60) and previous noncompliance (OR = 10.04; 95%CI: 7.37-13.68).

conclusionUp to 14% of European patients are not retreated after

Indexed as

Anti-Bacterial AgentsHelicobacter InfectionsHelicobacter pyloriAgedAge FactorsDrug Therapy, CombinationEuropeFemaleHumansMaleMiddle AgedProspective StudiesProton Pump InhibitorsRegistriesRetreatmentTreatment FailureAnti-Bacterial AgentsProton Pump InhibitorsEradication failureEradication treatmentEuropean registry on Helicobacter pylori managementHelicobacter pyloriRetreatment

Identifiers

PMID41694498
PMCPMC12897957

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.