Evidence map›Paper›PMID 41694497›Full record

ArticleWorld journal of gastroenterology2026

Twenty-year temporal trends, risk profiles, and prognostic value of clinicopathological features in gallbladder cancer following cholecystectomy.

Jeongyeon An, So-Hyun Ahn, Kyung-Hee Kim, Jun Young Heo, Min-Kyung Yeo

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Article in World journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jeongyeon AnDepartment of Pathology, Chungnam National University School of Medicine, Daejeon 35015, South Korea.
So-Hyun AhnDepartment of Psychiatry, Chungnam National University School of Medicine, Daejeon 35015, South Korea.
Kyung-Hee KimDepartment of Pathology, Chungnam National University School of Medicine, Daejeon 35015, South Korea.
Jun Young HeoSystem Network Inflammation Control Research Center, Chungnam National University, Daejeon 35015, South Korea.
Min-Kyung YeoDepartment of Pathology, Chungnam National University School of Medicine, Daejeon 35015, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGallbladder cancer (GBC) is a rare but highly aggressive malignancy often diagnosed at an advanced stage. Owing to its relatively low incidence, the clinicopathologic features of GBC and its precursor lesions remain poorly understood and insufficiently explored.

aimTo examine temporal trends and clinicopathological features in post-cholecystectomy GBC to identify risks profiles and prognostic value.

methodsIn this retrospective study, 15785 patients who underwent cholecystectomy over a 20-year period at a single center were reviewed, among whom 285 were diagnosed with GBC. Clinicopathological features were compared among patients with benign conditions, precursor lesions, and GBC. Long-term temporal trends (2004-2023) were analyzed alongside clinicopathological characteristics and survival outcomes.

resultsGBC cases increased over time (

conclusionThe clinicopathologic characteristics of GBC highlight the value of recognizing high-risk profiles and underscore the prognostic significance of detailed histopathological evaluation.

Indexed as

CholecystectomyGallbladder NeoplasmsAdultAgedAged, 80 and overFemaleGallbladderHumansIncidenceMaleMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesRisk FactorsTime FactorsCholecystectomyGallbladder cancerPrognosisRisk factorsTime factors

Identifiers

PMID41694497
PMCPMC12898658

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.