ArticleTransplantation direct2026
Effect of Donor-Recipient Age Difference on Liver Transplant Outcomes.
Article in Transplantation direct, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Influence of donor-recipient age differences in allogenic rat thyroid transplantation.Regenerative therapy · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The global organ shortage and aging population lead to the use of liver grafts with increasing donor-recipient age discrepancies. This study evaluated the impact of donor-recipient age mismatch on posttransplant outcomes. Methods: Organ Procurement and Transplantation Network/United Network for Organ Sharing data were analyzed, stratifying donor-to-recipient pairs by age difference: young-to-old (≥20 y), old-to-young (≥20 y), and similar-age group (<20 y difference). Liver life expectancy was calculated by adding recipient survival time to donor age. Graft survival was assessed using Kaplan-Meier and Cox regression analyses. Results: Among 111 125 liver transplantation recipients performed between 2005 and 2024, young-to-old group (≥20 y younger) had the highest 5-y graft survival (77.8%), followed by similar-age group (76.0%). Old-to-young group (≥20 ys older) had the lowest survival (69.9%) ( Conclusions: A greater donor-to-recipient age difference, particularly with older donors, negatively impacted liver graft survival. However, patient survival was not affected, supporting the use of older grafts to optimize transplant benefits for selected recipient populations.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.