ArticleNutrition research and practice2026
Comparative analysis of lipid-lowering effects of edible insects (
Article in Nutrition research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesEdible insects are increasingly being recognized as sustainable protein sources with potential lipid-lowering properties. In this study, we investigated the effects of protein hydrolysates from 3 edible insects, MATERIALS/
methodsTreat cells with different concentrations of insect hydrolysates for 48 h during adipocyte differentiation. To evaluate the lipid-lowering effects of insect hydrolysates, analyses were conducted using Oil Red O staining, western blotting and quantitative real-time polymerase chain reaction.
resultsNon-toxic concentrations (0.25, 0.5, and 1 mg/mL) of the hydrolysates were applied during adipocyte differentiation for 48 h. All 3 hydrolysates significantly reduced intracellular lipid accumulation, with the PB hydrolysate demonstrating superior effects. PB uniquely stimulated lipolysis, as indicated by increased free fatty acid and glycerol release, accompanied by enhanced phosphorylation of hormone-sensitive lipase. Additionally, the PB hydrolysate upregulated key genes involved in adipocyte metabolism, including
conclusionPB hydrolysate exhibits distinct metabolic benefits, highlighting its potential as a functional food ingredient for obesity management. Further
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