ArticleOrthopedic reviews2026
Vascularized Nerve Grafts: Current Concepts, Indications, and Future Perspectives.
Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Extracellular Matrix Remodelling in the Human Sural Nerve in Peripheral Vascular Disease.Medicina (Kaunas, Lithuania) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peripheral nerve injuries pose significant challenges due to limited regenerative capacity and functional recovery, especially in large or complex defects. Traditional repair methods using non-vascularized autologous nerve grafts often result in suboptimal outcomes due to ischemia-induced central necrosis and delayed axonal regeneration. Vascularized nerve grafts (VNGs), which provide an intrinsic blood supply, have emerged as a promising alternative to enhance nerve repair by improving graft survival, supporting Schwann cell viability, and promoting early neovascularization. This review on vascularized nerve grafting examines its advantages, challenges, and emerging experimental approaches. VNGs demonstrate superior functional outcomes compared to non-vascularized grafts, with improved motor and sensory recovery, and higher axonal density, particularly in long-gap and delayed repairs. Although the use of vascularized nerve grafts is limited by technical complexity, increased operative time, and donor site morbidity. In this study we aim to provide a comprehensive overview of the rationale, outcomes, and challenges associated with vascularized nerve grafts, while highlighting emerging experimental strategies poised to overcome current limitations in peripheral nerve repair.
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Registered trials
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