Evidence map›Paper›PMID 41694335›Full record

ArticleFrontiers in immunology2026

Single-cell transcriptomics of Pacific white shrimp (

Johanna E Aldersey, Jason W Abernathy, Miles D Lange, Julio C García, Craig A Shoemaker, Benjamin H Beck

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Frontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johanna E AlderseyARS Research Participation Program, Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN, United States.
Jason W AbernathyUnited States Department of Agriculture, Agricultural Research Service, Aquatic Animal Health Research Unit, Auburn, AL, United States.
Miles D LangeUnited States Department of Agriculture, Agricultural Research Service, Aquatic Animal Health Research Unit, Auburn, AL, United States.
Julio C GarcíaUnited States Department of Agriculture, Agricultural Research Service, Aquatic Animal Health Research Unit, Auburn, AL, United States.
Craig A ShoemakerUnited States Department of Agriculture, Agricultural Research Service, Aquatic Animal Health Research Unit, Auburn, AL, United States.
Benjamin H BeckUnited States Department of Agriculture, Agricultural Research Service, Aquatic Animal Health Research Unit, Auburn, AL, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The shrimp aquaculture industry is severely impacted by acute hepatopancreatic necrosis disease (AHPND) caused by the bacterium Methods: First, hepatopancreas from three healthy Pacific white shrimp ( Results: The atlas consists of 11,006 quality cells that were grouped into nine clusters, and represent the hepatopancreas epithelial cells, myocytes and hemocytes. The infection study generated 16,368 quality cells and was integrated with the atlas for 27,374 cells grouped into nine clusters. Cells from the infected shrimp exhibited expression of immune related genes including diverse pathogen recognition receptors and humoral proteins, including hemocyanin, proteases and C-type lectins. We also found that cells expressed factors that the PirA/B toxins present in the infective Conclusions: We characterized the cells types of the hepatopancreas and examined the transcriptomic response to a virulent isolate of

Indexed as

HepatopancreasPenaeidaeTranscriptomeVibrio InfectionsVibrio parahaemolyticusAnimalsGene Expression ProfilingHost-Pathogen InteractionsImmunity, InnateSingle-Cell AnalysisSingle-Cell Gene Expression Analysisacute hepatopancreatic necrosis diseaseaquaculturehepatopancreashost-pathogen interactionLitopenaeus vannameishrimpsingle-cell transcriptomicsVibrio parahaemolyticus

Identifiers

PMID41694335
PMCPMC12902777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.