Evidence map›Paper›PMID 41694308›Full record

ArticleFrontiers in cardiovascular medicine2026

Qing-Xin-Jie-Yu granule prevents myocardial infarction-induced apoptosis via inhibition of p38 MAPK pathway.

Jianghan Qi, Qiaoyan Cai, Ying Han, Xiaoyao Gao, Meiling Yang, Chenyi Wei, Keyi Wang, Zhenghao Lyu, Yuxing Lin, Ling Zhang and 2 more

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jianghan Qi *College of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Qiaoyan Cai *College of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Ying HanCollege of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Xiaoyao GaoCollege of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Meiling YangDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Chenyi WeiCollege of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Keyi WangCollege of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Zhenghao LyuCollege of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Yuxing LinCollege of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Ling ZhangCollege of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Zhuye GaoCardiovascular Diseases Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jianfeng ChuCollege of Integrative Medicine, Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Myocardial infarction (MI) is a leading cause of death globally, and traditional Chinese medicine (TCM) offers therapeutic potential through its multi-targeted approach. This study aims to investigate the protective mechanisms of Qing-Xin-Jie-Yu Granule (QXJYG) against MI. Methods: Network pharmacology was carried out to predict targets and pathways of QXJYG in the treatment of MI. An Results: GO and KEGG analyses suggest that QXJYG affects potential targets related to cellular oxidative stress and apoptosis in MI. Conclusions: This study demonstrates that QXJYG exerts cardioprotective effects against MI by improving cardiac function, reducing oxidative stress, and inhibiting apoptosis through the regulation of the p38 MAPK signaling pathway both

Indexed as

apoptosismyocardial infarctionnetwork pharmacologyp38 MAPK pathwayqing-Xin-Jie-Yu granule

Identifiers

PMID41694308
PMCPMC12901470

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.