ArticleFrontiers in cardiovascular medicine2026
Nomogram prediction model for pneumonia after valve replacement in patients with heart valve disease.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Patients with heart valve disease (VHD) combined with pulmonary hypertension (PH) have a higher risk for hospital-acquired pneumonia. We aimed to analyze the risk factors and construct a valid nomogram model for predicting hospital-acquired pneumonia among those patients. Methods: Patients with VHD combined with PH who underwent heart valve replacement were collected. The perioperative risk factors for hospital-acquired pneumonia were analyzed by univariable and logistic regression, and then a nomogram prediction model was constructed and validated. Results: A total of 377 patients were included, and 81 cases developed postoperative hospital-acquired pneumonia, with an incidence of 21.49%. The results of multifactorial analysis showed that preoperative anemia, ASA score >grade III, duration of surgery ≥313 min, duration of endotracheal intubation ≥3 d, duration of indwelling gastric tube ≥1 d, and bioprosthetic valve usage were the risk factors for the occurrence of postoperative hospital-acquired pneumonia ( Conclusions: The constructed six-variable nomogram prediction model has satisfying efficacy in predicting hospital-acquired pneumonia after valve replacement in patients with VHD combined with PH. It is significant for early identification and future quality improvement to reduce the risk of hospital-acquired pneumonia.
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