Evidence map›Paper›PMID 41694291›Full record

ArticleTherapeutic advances in endocrinology and metabolism2026

Impacts of insulin storage and injection techniques intervention on glycemic control among patients with diabetes in northwest Ethiopia: a quasi-experimental study.

Samuel Berihun Dagnew, Woretaw Sisay Zewdu, Samuel Agegnew Wondm, Tilaye Arega Moges, Fisseha Nigussie Dagnew, Sisay Sitotaw Anberbr, Getachew Yitayew Tarekegn, Tigabu Eskeziya Zerihun, Desalegn Addis Mussie, Abel Temeche Kassaw and 6 more

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Article in Therapeutic advances in endocrinology and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

16 authors.

Samuel Berihun DagnewDepartment of Clinical Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor 6300, Ethiopia.ORCID https://orcid.org/0000-0002-8938-4551
Woretaw Sisay ZewduDepartment of Pharmacology, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Samuel Agegnew WondmDepartment of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Tilaye Arega MogesDepartment of Clinical Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Fisseha Nigussie DagnewDepartment of Clinical Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Sisay Sitotaw AnberbrDepartment of Pharmacy, College of Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia.
Getachew Yitayew TarekegnDepartment of Clinical Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Tigabu Eskeziya ZerihunDepartment of Clinical Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Desalegn Addis MussieDepartment of Clinical Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Abel Temeche KassawDepartment of Clinical Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Azimeraw Siraw AzenegaMinistry of Health,Addis Ababa, Ethiopia.
Teferi Bihonegn MeleseDepartment of Clinical Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Getu Berihun DagnawMinistry of Health,Addis Ababa, Ethiopia.
Mitikie Wondmagegn MebratDepartment of Medical Microbiology, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Tirsit Ketsela ZelekeDepartment of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Taklo Simeneh YazieDepartment of Pharmacology, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Proper storage of insulin and accuracy of injection technique are essential for maintaining the effectiveness of insulin and optimizing glycemic control. In resource-poor countries like Ethiopia, poor storage conditions and incorrect injection techniques are prevalent, and hence, less than desired glycemic results are obtained. Interventional studies aimed at addressing these problems in Ethiopia are lacking. Objectives: This study aimed to evaluate the effect of an educational intervention on glycemic control, insulin storage behavior, and injection practices among diabetic patients at Debre Tabor Hospital. Design: A quasi-experimental pre- and post-intervention study design was employed. Methods: The study was conducted at Debre Tabor Hospital from January to June 2024. Baseline data on insulin storage, injection practices, and fasting blood glucose levels were collected using structured questionnaires and clinical records. The intervention was educational conferences with demonstrations and take-home materials on appropriate injection and storage practices. A follow-up after 3 months was carried out to determine changes in glycemic control and practice change. The intervention's efficacy was determined by analyzing data using STATA version 17 with logistic regression and McNemar's test. Results: There were 330 diabetic patients enrolled with a mean age of 42.87 ± 13.76 years, of which 59.39% had type 1 diabetes. Insulin injection technique improved from 48.68% to 72.46% following the intervention ( Conclusion: The educational intervention successfully enhanced the insulin injection and storage procedures, thereby achieving improved glycemic control results. However, glycemic outcomes were still adversely affected by enduring factors of age and polypharmacy. This justifies the need for continuous education and individualized interventions to handle both unchangeable patient factors and mutable behaviors.

Indexed as

diabetes mellituseducational interventionglycemic controlinjection techniquesinsulin storage

Identifiers

PMID41694291
PMCPMC12905103

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.