Evidence map›Paper›PMID 41694197›Full record

ReviewIranian endodontic journal2026

Magnesium Phosphate Cements for Endodontic Applications: A Critical Review of Promise and Pitfalls.

Nishmitha N Hegde, Harshitha Somanatha, Chaithra Lakshmi V, Mithra N Hegde

Abstract readReview
In one paragraph

Review in Iranian endodontic journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nishmitha N HegdeDepartment of Conservative Dentistry and Endodontics, AB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India.
Harshitha SomanathaAB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India.
Chaithra Lakshmi VAB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India.
Mithra N HegdeAB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnesium phosphate cements (MPCs) have recently gained attention as potential materials for endodontic applications due to their rapid setting, favourable mechanical properties, and bioactive potential. Laboratory and preclinical studies indicate that MPCs can form apatite-like structures, exhibit good compressive strength, and support cell viability, suggesting promising biological interactions. However, several limitations remain unresolved. The acid-base setting reaction of MPCs is strongly exothermic, which may pose a risk to pulp or periapical tissues, and ammonium-containing formulations can release cytotoxic ammonia, although partial mitigation is possible through sodium phosphate substitution. Rapid setting enhances handling in controlled conditions but may complicate placement in complex root canal anatomies. While

Indexed as

Bioactive CementsEndodontic BiomaterialsPulp CappingRegenerative EndodonticsRoot-end Filling

Identifiers

PMID41694197
PMCPMC12900526

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.