Evidence map›Paper›PMID 41694187›Full record

ArticlePrzeglad menopauzalny = Menopause review2025

Intraoperative margin assessment in breast-conserving surgery. Preliminary analysis of cost-effectiveness and organisational benefits.

Paweł Pyka, Dzmitry Karkotka, Paweł Kołodziej

Abstract read
In one paragraph

Article in Przeglad menopauzalny = Menopause review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paweł PykaDr. Alfred Sokołowski Specialist Hospital, Walbrzych, Poland.
Dzmitry KarkotkaDr. Alfred Sokołowski Specialist Hospital, Walbrzych, Poland.
Paweł KołodziejDr. Alfred Sokołowski Specialist Hospital, Walbrzych, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Breast-conserving surgery (BCS) is the standard treatment for early breast cancer, offering comparable oncological effectiveness to mastectomy with better aesthetic outcomes. Achieving negative surgical margins is essential, as positive margins increase the risk of recurrence and reoperation, which place a burden on both patients and the healthcare system.This retrospective study evaluated the effectiveness of intraoperative margin assessment in BCS, focusing on its impact on reducing reoperation rates and analysing financial and organisational benefits. Material and methods: Between 2016 and 2023, 549 patients underwent BCS with intraoperative margin assessment using frozen section analysis. Positive surgical margins were identified in 70 patients (12.8%). Through intraoperative re-excisions, negative margins were ultimately achieved in 55 cases, avoiding mastectomy or later reoperation. Only four patients (0.7%) required reoperation after the initial procedure. Results: Avoiding reoperation generated significant cost savings. The average cost of one reoperation was estimated at PLN 12,829 (approximately EUR 3,013) in centres without comprehensive oncological care and PLN 17,855 (approximately EUR 4,194) in centres with comprehensive oncological care. The total savings for avoided procedures amounted to PLN 898,045 (about EUR 210,918) and PLN 1,249,857 (about EUR 293,545), respectively. Conclusions: Intraoperative margin assessment during BCS is an effective strategy that minimises the need for repeated procedures, improves patient outcomes, and provides measurable economic benefits at the healthcare system level. Wider implementation of this method may help optimise surgical resources while enhancing the quality of care.

Indexed as

breast cancerbreast-conserving surgerycost-effectivenessintraoperative assessmentreoperationssurgical margins

Identifiers

PMID41694187
PMCPMC12895545

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.