ArticleFrontiers in psychiatry2025
Associations between cochlear electrophysiology, emotional health, and sleep quality in adults with tinnitus: a comprehensive analysis.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Tinnitus is commonly accompanied by emotional distress and sleep disturbances, yet the extent to which these characteristics relate to cochlear electrophysiologic findings remains unclear. This study examined associations between electrophysiologic measures and emotional and sleep parameters in adults with subjective tinnitus. Methods: This retrospective study included 120 adults with tinnitus. Data collected included demographics, cochlear electrophysiologic measures (electrocochleography and auditory brainstem response), emotional characteristics (perceived stress, depressive symptoms, anxiety, emotion regulation), and sleep parameters (sleep quality, insomnia severity, daytime sleepiness). Correlation analyses and multivariate regression models were applied. Results: The mean age of the cohort was 62.35 years (SD 9.45), and 64.17% were male. A very weak negative correlation was observed between depressive symptoms and Wave III latency (r = -0.196, P = 0.03), but the small magnitude suggests minimal explanatory value. The summating potential/action potential ratio was not significantly correlated with sleep quality (r = -0.181, P = 0.05). In multivariate models, anxiolytic use was associated with a lower risk of poor sleep (adjusted odds ratio [aOR] = 0.262; 95% confidence interval [CI]: 0.078-0.881; P = 0.030), whereas antidepressant use was associated with a higher risk (aOR = 2.628; 95% CI: 1.027-6.724; P = 0.044). For insomnia, higher pure-tone average thresholds (aOR = 0.948 per dB; 95% CI: 0.906-0.992; P = 0.007) and hearing aid use (aOR = 3.396; 95% CI: 1.085-10.623; P = 0.036) were significant determinants. The only significant factor associated with quality of life was tinnitus duration, with longer duration associated with lower WHOQOL-BREF scores (β = -2.74; P = 0.020). No electrophysiologic parameter demonstrated significant associations in the multivariate models. Conclusion: Within the constraints of this study, cochlear electrophysiologic measures showed limited observable associations with emotional or sleep characteristics. Factors related to hearing status and medication use demonstrated stronger statistical associations with sleep outcomes, while tinnitus duration was linked to quality-of-life scores. These findings contribute to the growing body of descriptive evidence on tinnitus-related characteristics, although further research with larger cohorts and longitudinal designs is needed to clarify these relationships.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.