ArticleFrontiers in psychiatry2025
Study on the effects of exercise intervention combined with virtual reality technology on emotions and brain networks in secondary school students with depressive symptoms.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of exercise interventions on EEG alpha power across different populations: a systematic review and meta-analysis.Frontiers in psychology · 2026Pooled it
- Electroencephalography Functional Network Responses to Immersive Virtual Reality in Alzheimer Disease and Mild Cognitive Impairment: Exploratory Single-Session 3-Group Repeated-Measures Study.JMIR serious games · 2026Article
- Exercise-induced neuropeptidergic and neurochemical neuroadaptation in stress regulation and emotional disorders.Acta neurologica Belgica · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aimed to investigate the functional connectivity characteristics of brain networks in secondary school students with depressive symptoms and to analyze the effects of exercise combined with virtual reality intervention on improving brain networks and emotional states, providing a neurobiological basis for early identification and precise intervention. Methods: This study recruited 98 middle school students aged 13 to 18 as research subjects, including 50 in the subclinical depression (ScD) group and 48 in the healthy control (HC) group. The experimental intervention employed a 2×3 two-way mixed design analysis of variance (Two-way ANOVA). All exercise intervention groups underwent 15 minutes of moderate-intensity (50%-80% HRmax) power cycling training. The exercise intervention combined with virtual reality technology group completed their training in an immersive natural landscape environment. Resting-state EEG signals were recorded before and after the intervention, and emotional state changes were assessed using the Positive and Negative Affect Schedule (PANAS). The cerebral cortex was segmented into 78 regions based on the Schaefer template. Phase-locked value ( Results: Exercise intervention combined with virtual reality technology significantly improved θ and α band SMN-DMN, DAN-SN connectivity, and DMN/DAN activity ( Conclusion: Depressive symptoms in adolescents are associated with multifrequency brain network dysregulation. Combining exercise intervention with virtual reality technology (VR-EI) optimizes key brain network connectivity and activity in the theta and alpha bands through multisensory stimulation. Its mood-enhancing effects surpass those of conventional exercise, offering a promising new strategy for personalized intervention in adolescent depression.
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