ReviewJournal of clinical and translational science2026
Factors influencing the performance of clinical research networks to improve the success of cancer clinical trials: A scoping review and organizational analysis.
Review in Journal of clinical and translational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer clinical research networks (CRNs) play a vital role in medical research globally by generating investigator-initiated research, pooling expertise, and enabling recruitment across multiple sites. Completing clinical trials is challenging. Delays can slow the generation of evidence needed to refine the best patient treatments. The aim of this review was to identify factors that have been either proposed or shown by research to influence the performance of cancer CRNs to improve trial success, outcomes and impact. A scoping review was conducted using a systematic search across five databases [PROSPERO CRD42023414241]. Records were screened for eligibility. For included articles, data on factors and research methods were extracted independently by up to three reviewers, and disagreements resolved by discussion. 1928 articles were returned, 13 were included. Articles reported on 11 membership-based cancer CRNs with headquarters in four countries (eight in the USA). Factors influencing CRN performance broadly fell into six categories: site, CRN, patient, regulatory, policy and industry factors, with subcategories in each case. These findings may help to inform future research to prioritize and improve the day-to-day performance of membership-based cancer CRNs and other trial sponsors to optimize clinical trial success. Further research is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.