Evidence map›Paper›PMID 41693919›Full record

ArticleCase reports in hematology2026

Splenic Embolization to Manage Thrombocytopenia in Cancer Patients: Case Reports and Review of the Literature.

Zahra Ridha, Kiat Tsong Tan, Michael Connolly, Radhika Yelamanchili, Rachel VanderMeer, Mohammad Refaei

Abstract read
In one paragraph

Article in Case reports in hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zahra RidhaNiagara Regional Campus, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Canada, mcmaster.ca.ORCID https://orcid.org/0009-0008-3147-7297
Kiat Tsong TanMedical Imaging Department, Niagara Health, St. Catharines, Canada.
Michael ConnollyRadiology Department, McMaster University, Hamilton, Canada, mcmaster.ca.
Radhika YelamanchiliOncology, McMaster University, Hamilton, Canada, mcmaster.ca.
Rachel VanderMeerOncology, McMaster University, Hamilton, Canada, mcmaster.ca.
Mohammad RefaeiDoM Hematology and Thromboembolism, McMaster University, Hamilton, Canada, mcmaster.ca.ORCID https://orcid.org/0000-0002-7315-2836

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombocytopenia is a common complication of cancer and its management. Platelet count guides patients' cancer treatment, as a safe threshold is required before initiating a chemotherapy regimen. Preventing thrombocytopenia in cancer patients is essential to avoid dose reduction or delay of chemotherapy. Partial splenic embolization (PSE) is a procedure that can increase platelet count in cancer patients, allowing them to initiate/resume chemotherapy and receive other treatments such as surgery and tumor ablation. Herein, we report two cases of cancer patients that underwent a PSE to improve thrombocytopenia in order to receive chemotherapy. One patient had a successful procedure, although they had a recurrence of thrombocytopenia 18 months later requiring repeat PSE. The other patient suffered serious complications as a result of unintentional total embolization of the spleen and the tail of the pancreas, resulting in necrotizing pancreatitis that rendered her unable to start chemotherapy. We analyzed both cases to provide insight on the safety and effectiveness of the procedure for cancer patients.

Indexed as

cancerchemotherapyinterventional radiologypartial splenic embolizationthrombocytopenia

Identifiers

PMID41693919
PMCPMC12905002

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.