Evidence map›Paper›PMID 41693905›Full record

ArticleBiomedical optics express2026

Predicting wrist osteoporosis from excised human finger bones using spatially offset Raman spectroscopy - a cadaveric study.

Mohammad Hosseini, Sadia Afrin, Anthony Yosick, Emma Schenker, Hani Awad, Andrew J Berger

Abstract read
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Mohammad HosseiniThe Institute of Optics, University of Rochester, 275 Hutchison Rd, Rochester, NY 14620, USA.ORCID https://orcid.org/0000-0002-3508-0851
Sadia AfrinDepartment of Biomedical Engineering, University of Rochester, 207 Robert B. Goergen Hall, Rochester, NY 14620, USA.
Anthony YosickDepartment of Biomedical Engineering, University of Rochester, 207 Robert B. Goergen Hall, Rochester, NY 14620, USA.
Emma SchenkerThe Institute of Optics, University of Rochester, 275 Hutchison Rd, Rochester, NY 14620, USA.
Hani AwadDepartment of Biomedical Engineering, University of Rochester, 207 Robert B. Goergen Hall, Rochester, NY 14620, USA.
Andrew J BergerThe Institute of Optics, University of Rochester, 275 Hutchison Rd, Rochester, NY 14620, USA.ORCID https://orcid.org/0000-0001-5090-1198

Funding

Rochester Resource-Based Center for Bone, Muscle and Orthopaedic Research (ROCSTARR) (Overall Application)P30AR069655 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2016 to 2026
$7.8M
Raman spectroscopic platform for transcutaneous monitoring of bone qualityR01AR070613 · NIAMS · UNIVERSITY OF ROCHESTER · PI Hani A Awad, ANDREW J BERGER · 2016 to 2026
$4.0M
NIAMS NIH HHS P30 AR069655NIAMS NIH HHS R01 AR070613
6 · The paper itself

Abstract

Osteoporosis and osteopenia remain vastly underdiagnosed. Current clinical screening relies almost exclusively on dual-energy X-ray absorptiometry (DXA), which measures bone mineral density (BMD) but fails to capture the compositional changes that lead to BMD loss. We investigated whether spatially offset Raman spectroscopy (SORS) applied to excised finger bones can assess subsurface biochemical markers associated with bone health and estimate wrist DXA T-scores. Raman spectra were acquired

Identifiers

PMID41693905
PMCPMC12904550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.