ArticleBiomedical optics express2026
Computational framework for combining multiple swept-sources for high-resolution in-vivo optical coherence tomography.
Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Axial resolution in swept-source-based Fourier-domain optical coherence tomography (FD-OCT) is limited by the sweep range of the source. However, broad swept-sources are not readily available, and passively combining two laser sources is not straightforward. In this paper, we develop a framework to overcome this limit by computationally combining independently sweeping sources to increase the bandwidth and subsequently the axial resolution of full-field Fourier-domain optical coherence tomography (FF-FD-OCT) systems. To this end, we demonstrate a dual-laser full-field FD-OCT system that uses two lasers, which sweep sequentially and are stitched phase-correctly in post-processing to obtain high-bandwidth spectra. After combining, we achieve an effective bandwidth of 145 nm at a central wavelength of 878 nm. The system has a high axial resolution of 3.1
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