Evidence map›Paper›PMID 41693900›Full record

ArticleBiomedical optics express2026

Label-free tracking of subcortical white matter degradation

Nicole E Chernavsky, Nuri Hong, Lianne J Trigiani, Nozomi Nishimura, Chris B Schaffer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicole E ChernavskyMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID https://orcid.org/0009-0008-4128-0498
Nuri HongMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
Lianne J TrigianiMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
Nozomi NishimuraMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID https://orcid.org/0000-0003-4342-9416
Chris B SchafferMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID https://orcid.org/0000-0002-7800-9596

Funding

Laser and Microscope Development for Multicolor Nonlinear Imaging Deep in TissueR01EB002019 · NIBIB · CORNELL UNIVERSITY ITHACA · PI WISE, FRANK W · 2003 to 2019
$4.1M
ApoE4, Neurovascular Injury and Cognitive ImpairmentR01NS126467 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Costantino Iadecola · 2022 to 2026
$4.1M
Damage Associated Molecular Patterns and Regenerative Failure in MSR01NS104350 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI VARTANIAN, TIMOTHY · 2018 to 2022
$1.8M
High-Speed Imaging of Cortical and White Matter Microvascular Flow in AD/ADRD ModelsR01NS128947 · NINDS · CORNELL UNIVERSITY · PI Costantino Iadecola, CHRIS B SCHAFFER · 2025 to 2026
$1.6M
NIBIB NIH HHS R01 EB002019NINDS NIH HHS R01 NS104350NINDS NIH HHS R01 NS126467NINDS NIH HHS R01 NS128947
6 · The paper itself

Abstract

Characterization of myelin degradation in the white matter (WM) is important for understanding neurodegeneration. We demonstrate label-free

Identifiers

PMID41693900
PMCPMC12904527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.