Copolymers of NVAm and NVP for Efficient Gene Delivery.

Tom Fielitz, Christopher Raab, Vitalii Tkachenko, Kristine M Oleszkiewicz, Hendrik Fuchs, Matthias Hartlieb

Abstract read

In one paragraph

Article in ACS polymers Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tom FielitzInstitute of Chemistry, University of Potsdam, Karl-Liebknecht-Straße 24-25, Potsdam DE-14476, Germany.

Christopher RaabInstitute of Diagnostic Laboratory Medicine, Clinical Chemistry and Pathobiochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, Berlin DE-13353, Germany.

Vitalii TkachenkoInstitute of Chemistry, University of Potsdam, Karl-Liebknecht-Straße 24-25, Potsdam DE-14476, Germany.

Kristine M OleszkiewiczInstitute of Diagnostic Laboratory Medicine, Clinical Chemistry and Pathobiochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, Berlin DE-13353, Germany.

Hendrik FuchsInstitute of Diagnostic Laboratory Medicine, Clinical Chemistry and Pathobiochemistry, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, Berlin DE-13353, Germany.ORCID https://orcid.org/0000-0001-9153-9594

Matthias HartliebInstitute of Chemistry, University of Potsdam, Karl-Liebknecht-Straße 24-25, Potsdam DE-14476, Germany.ORCID https://orcid.org/0000-0001-5330-7186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene delivery lies at the heart of many approaches for treating a host of different diseases. Promising candidates for the delivery of genetic material are polycationic vectors; however, managing toxicity arising from adverse interactions with the lipid bilayer remains a challenge. In this work, photoiniferter reversible addition-fragmentation chain-transfer (PI-RAFT) polymerization was used to synthesize statistical copolymers of

Indexed as

charge density controlgene delivery vectorsN-vinyl formamidephotoiniferter RAFT polymerization (PI-RAFT)polyaminetransfection optimization

Identifiers

PMID41693817

DOI10.1021/acspolymersau.5c00167

PMCPMC12903468

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.