Evidence map›Paper›PMID 41693793›Full record

ReviewFrontiers in pharmacology2026

From venom peptides to neurotherapeutics: BmK defensins and short-chain peptides as modulators of ion channels.

Yin Dong, Jiajun Wang, Yudan Zhu, Lu Zhao, Yunqing Zeng, Lele Tang, Qian Xiao, Jiwei Cheng, Chao Wang, Jie Tao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yin Dong *Joint Laboratory of Nanxiang Branch of Ruijin Hospital-School of Life Sciences, Shanghai University, Shanghai, China.
Jiajun Wang *Joint Laboratory of Nanxiang Branch of Ruijin Hospital-School of Life Sciences, Shanghai University, Shanghai, China.
Yudan ZhuPutuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lu ZhaoPutuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yunqing ZengPutuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lele TangPutuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Qian XiaoPutuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jiwei ChengPutuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Chao WangJoint Laboratory of Nanxiang Branch of Ruijin Hospital-School of Life Sciences, Shanghai University, Shanghai, China.
Jie TaoJoint Laboratory of Nanxiang Branch of Ruijin Hospital-School of Life Sciences, Shanghai University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scorpions, having inhabited the Earth long before the emergence of humans, represent an ancient lineage of arthropods. While often regarded with fear due to their potential to induce severe pain or fatal envenomation, scorpion venoms constitute complex cocktails of bioactive molecules known as toxins. Notably, these toxic components have been repurposed in medical research as valuable sources for therapeutic development. In traditional Chinese medicine (TCM), the venom of

Indexed as

BMKchloride channelsdefensinneurological diseasepotassium channelsshort chain toxinTRP channels

Identifiers

PMID41693793
PMCPMC12894229

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.