Evidence map›Paper›PMID 41693741›Full record

ArticleDEN open2026

Feasibility Study of Modified Underwater Endoscopic Mucosal Resection for Colorectal Polyps.

Kaizo Kagemoto, Koichi Okamoto, Yoji Takeuchi, Yasuyuki Okada, Motoko Sei, Shota Fujimoto, Ryo Shinomiya, Takeshi Mitsuhashi, Takanori Yoshimoto, Reiko Yokoyama and 8 more

Abstract read
In one paragraph

Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Kaizo KagemotoDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.ORCID https://orcid.org/0000-0003-3524-2053
Koichi OkamotoDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Yoji TakeuchiDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.ORCID https://orcid.org/0000-0003-3814-298X
Yasuyuki OkadaDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Motoko SeiDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Shota FujimotoDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Ryo ShinomiyaDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Takeshi MitsuhashiDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Takanori YoshimotoDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Reiko YokoyamaDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Tomoyuki KawaguchiDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Yoshifumi KidaDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Yasuhiro MitsuiDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Yutaka KawanoDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Masahiro SogabeDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Hiroshi MiyamotoDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Yasushi SatoDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.
Tetsuji TakayamaDepartment of Gastroenterology and Oncology Institute of Biomedical Sciences Tokushima University Graduate School Tokushima Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Underwater endoscopic mucosal resection (UEMR) is widely performed for colorectal tumors. However, in our experience, it is sometimes difficult to keep a clear endoscopic view underwater, due to dirty fluid inflow or insufficient water pooling after grasping the polyp, or bleeding just after endoscopic resection. To compensate for such challenges, we reported modified UEMR (M-UEMR) as a procedure for snaring underwater and undergas resection. Therefore, we conducted a prospective clinical trial to investigate the safety and efficacy of M-UEMR. Methods: This single-center prospective study was conducted at Tokushima University Hospital. Patients with 10-25 mm colorectal polyps were enrolled. The polyps were snared underwater, then infused water was removed, and the lumen was inflated with CO Results: Forty patients were enrolled, and the R0 resection rate was 80% (95% confidence interval [CI]: 64.4-90.9). No procedure-related adverse events were observed. En bloc resection was 92.5% (95% CI: 79.6-98.4). The median thickness of SM tissue (range) was 574 µm (241-2632) at the center of the specimen. Conclusion: M-UEMR demonstrated a high R0 resection rate with a safe profile. M-UEMR is expected to be utilized as an alternative technique to UEMR for colorectal polyps in patients with difficulty maintaining a clear visual field.

Indexed as

colorectal polypsmodified UEMRsubmucosal tissue thicknessUEMRunderwater

Identifiers

PMID41693741
PMCPMC12906297

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.