Evidence map›Paper›PMID 41693730›Full record

ArticleTransboundary and emerging diseases2026

Wesselsbron Virus-Induced Hepatitis in Ewes and Lambs Unraveled Through Machine Learning-Driven Digital Histopathology.

Llorenç Grau-Roma, Simone de Brot, Marta Zimoch, Loane Clerc, Noelle Donzé, Matthias Liniger, Francisco Brito, Adrián Herrera, Aurélie Godel, Artur Summerfield and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transboundary and emerging diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Llorenç Grau-RomaCOMPATH, Institute of Animal Pathology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, Bern, 3012, Switzerland, unibe.ch.ORCID https://orcid.org/0000-0002-9406-8844
Simone de BrotCOMPATH, Institute of Animal Pathology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, Bern, 3012, Switzerland, unibe.ch.ORCID https://orcid.org/0000-0003-3049-0103
Marta ZimochDepartment of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland, unibe.ch.ORCID https://orcid.org/0009-0006-9839-6577
Loane ClercCOMPATH, Institute of Animal Pathology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, Bern, 3012, Switzerland, unibe.ch.
Noelle DonzéDepartment of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland, unibe.ch.
Matthias LinigerDepartment of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland, unibe.ch.
Francisco BritoDepartment of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland, unibe.ch.ORCID https://orcid.org/0000-0003-1404-9799
Adrián HerreraCOMPATH, Institute of Animal Pathology, Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Länggassstrasse 122, Bern, 3012, Switzerland, unibe.ch.
Aurélie GodelDepartment of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland, unibe.ch.
Artur SummerfieldMultidisciplinary Center for Infectious Diseases, University of Bern, Bern, Switzerland, unibe.ch.ORCID https://orcid.org/0000-0001-8292-4634
Charaf BenarafaMultidisciplinary Center for Infectious Diseases, University of Bern, Bern, Switzerland, unibe.ch.ORCID https://orcid.org/0000-0002-2049-7769
Obdulio García-NicolásMultidisciplinary Center for Infectious Diseases, University of Bern, Bern, Switzerland, unibe.ch.ORCID https://orcid.org/0000-0001-8922-5449

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wesselsbron virus (WSLV) disease is an important neglected cause of hepatitis in ruminants with potential for zoonotic transmission, yet its histological lesions have been scarcely studied. We performed a thorough machine learning-driven, pathologist-led digital histopathological assessment of WSLV-induced hepatitis in ewes and lambs infected with clade I (rSA999) (

Indexed as

Hepatitis, Viral, AnimalMachine LearningSheep DiseasesAnimalsFemaleLiverSheepflavivirushepatitisimmunohistochemistrymachine learningquantificationruminantszoonosis

Identifiers

PMID41693730
PMCPMC12894784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.